It can be difficult to figure out what constitutes a typical poisonous or lethal dose. Nonetheless, the lethal oral dose of codeine in an adult is claimed to get within the number of 0.

Just take this medication by mouth with or without food stuff as directed by your health practitioner, ordinarily every four to 6 hours as desired. This medication is usually taken with foods if abdomen upset happens. Drink plenty of fluids after you use this medication Except if or else directed by your doctor.

Codeine: A research in rats and rabbits described no teratogenic influence of codeine administered throughout the duration of organogenesis in doses starting from five to one hundred twenty mg/kg. Inside the rat, doses within the a hundred and twenty-mg/kg degree, while in the toxic range for your Grownup animal, ended up linked to a rise in embryo resorption at time of implantation.

Because of the possibility of respiratory despair, prevent the use of opioid antitussives, which include Promethazine HCl and Codeine Phosphate Oral Answer in patients with compromised respiratory purpose, patients susceptible to respiratory failure, As well as in aged, cachectic, or debilitated clients.

Drug interactions, including a heightened incidence of extrapyramidal outcomes, are described when some MAOI and phenothiazines are made use of concomitantly.

Understand that this medication is prescribed since your health practitioner has judged which the profit to you is larger than the risk of Negative effects. Lots of individuals working with this medication would not have serious Unwanted effects.

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Stimulation can be Promethazine codeine syrup obvious, specifically in children and geriatric individuals. Convulsions may possibly almost never manifest. A paradoxical response has long been described in little ones acquiring single doses of 75 mg to one hundred twenty five mg orally, characterised by hyperexcitability and nightmares.

Promethazine may decreased seizure threshold. It ought to be used with warning in folks with seizure Ailments or in folks that are making use of concomitant prescription drugs, for example narcotics or area anesthetics, which may also have an affect on seizure threshold.

Side effects that typically usually do not call for professional medical awareness (report back to your treatment team should they continue or are bothersome):

If you are quite sleepy or have issues waking up just after employing this medication, prevent taking this medication and discuss with your health practitioner or pharmacist instantly. Your dosage may well must be lessen.

This medicine is taken only when desired, so there won't be any Unique Guidance for the missed dose. Dosing The dose of the drugs are going to be different for various patients. Comply with your medical professional's orders or the directions to the label. The subsequent data includes only the normal doses of this drugs. Should your dose is different, don't modify it Except if your doctor informs you to take action.

Promethazine and codeine might trigger marked drowsiness or may perhaps impair the mental and/or physical capabilities necessary to the overall performance of probably harmful duties, like driving a motor vehicle or operating machinery.

Usually do not suddenly cease taking your medication because you might establish a intense response. Your entire body turns into accustomed to the medication. This does NOT mean you might be addicted. Dependancy is a habits linked to obtaining and using a medication to get a nonmedical purpose.